Cover Image

Syntheses, Characterization, Crystal Structures and Antimicrobial Activity of 4-Bromo-N'-(pyridin-2-ylmethylene)benzohydrazide and Its Cobalt(III) and Manganese(II) Complexes

Yao Tan

Abstract


A new hydrazone compound 4-bromo-N'-(pyridin-2-ylmethylene)benzohydrazide (HL) and its cobalt(III) and manganese(II) complexes, [CoL2]NO3·2H2O (1) and [MnL2] (2) were prepared. They were characterized by a variety of physicochemical techniques. Molecular structures of the compounds were further confirmed by single crystal X-ray crystallography. The coordination geometry around the cobalt atom in complex 1 and the manganese atom in complex 2 are octahedral, with two pyridine N atoms, two imino N atoms, and two enolate O atoms from the ligands. The compounds were evaluated for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescence) and antifungal (Candida albicans and Aspergillus niger) activities by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method.


Keywords


Hydrazone; Cobalt complex; Manganese complex; Crystal structure; Antimicrobial activity

Full Text:

PDF


DOI: http://dx.doi.org/10.17344/acsi.2019.5297

Refbacks

  • There are currently no refbacks.


Copyright (c) 2019 Yao Tan

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.